Biomathematics

Past Graduates

Student

Doctoral dissertation title

Mentor(s)

Year

Risch, Neil J.

Theoretical and statistical analysis of chiasma distributions, recombination, and gene mapping.

Lange, K.

Spence, M.

1979

Landaw, Elliot M.

Optimal experimental design for biologic compartmental systems with applications to pharmacokinetics.

Newton, C.

Jennrich, R.

1980

Boehnke, Michael L.

Advances in pedigree analysis: ascertainment, goodness of fit, and optimization.

Lange, K.

Spence, M.

1983

Carson, Richard E.

Two image-wide parameter estimation methods for positron emission tomography: theory and application to the measurement of local cerebral blood flow in humans.

Huang, S.

1983

Louy, Charles.

Mathematical models of oxygen diffusion in skeletal and cardiac muscle and role of myoglobin: with applications to experiments on oxygen consumption and solubility in muscle.

Peskoff, A.

1983

Holmes, William R.

Cable theory modeling of the effectiveness of synaptic inputs in cortical pyramidal cells.

Newton, C.

Woody, C.

1986

Michelson, Seth G.

Two-compartment stochastic models for tumor escape.

Newton, C.

1987

Bahn, Mark M.

Studies of ligand-neuroreceptor binding with dynamic In vivo human and primate positron emission tomography data: model definition, validation, and parameter estimation.

Huang, S.

1988

Weeks, Daniel E.

New mathematical methods for human gene mapping.

Lange, K.

1988

Gambhir, Sanjiv.

Quantitation of the physical factors affecting the tracer kinetic modeling of cardiac positron emission tomography data.

Huang, S.

1990

Mahoney, Donald K.

Effects of neuroreceptor clustering on ligand binding kinetics in positron emission tomography.

Huang, S.

1990

Chen, Kewei

Estimation methods that account for measurement characteristics and statistical noise of input function in quantitative dynamic PET studies.

Huang, H.

1993

Sinsheimer, Janet S.

Extensions to evolutionary parsimony.

Little, R.

Lake, J.

1994

Sobel, Eric M.

Markov chain Monte Carlo methods in pedigree analysis: theoretical development and applications to location scores, variance component models, haplotyping, and marker allele sharing statistics.

Lange, K.

1996

Atri, Alireza

Mathematical modeling and analysis of intracellular calcium dynamics: oscillations and wave propagation.

Sneyd, J.

1996

Walker, Wynn L.

Computational design of minor groove binding sequence reading molecules and a mathematical analysis of their sequence binding properties.

Landaw, E.

Dickerson, E.

1997

Mower, William R.

Stress distributions in aortic aneurysms: factors affecting risk of rupture.

Newton, C.

1998

Chudin, Eugene.

Instability of cardiac excitation wave propagation and intracellular calcium dynamics (computer simulation study).

Landaw E.

Kogan, B.

1999

Shapiro, Bruce E.

Electrophysiological model of gap-junction mediated cortical spreading depression including osmotic volume changes.

Newton, C.

2000

Dorman, Karin S.

Human immunodeficiency virus type 1 genome variability recombination and emergence of resistance.

Sinsheimer, J.

2001

Suchard, Marc A.

Model building and selection in Bayesian phylogenetic reconstruction.

Sinsheimer, J.

Weiss, R.

2002

Snedecor, Sonya J.

Mathematical models to evaluate the optimal treatment of HIV-1 infection and the response of drug-resistant variants.

Newton, C.

2002.

Schadt, Eric E.

Generalized mathematical models for the reconstruction of evolutionary trees.

Lange, K.

2002.

Green, Leeta A.

Quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using positron emission tomography and a tracer kinetic model for radiolabeled acyclic guanosine analogues.

Gambhir, S.

2003

Liao, Wei-Hsun

Mathematical techniques in object matching and computational anatomy: a new framework based on the level set method.

Huang, H.

2003

Klapstein, Kevin D.

Physical models of the activities of the E. coli DNA strand exchange protein RecA.

Bruinsma, R.

Chou, T.

2004

Shoghi-Jadid, Kooresh

Imaging Alzheimer's disease at PET's resolution: a critical analysis through simulation of beta-amyloid pathology.

Huang, H.

Barrio, J.

2005

Redelings, Benjamin

Joint Bayesian estimation of alignment and phylogeny.

Suchard, M.

2006

Minin, Volodymy

Exploring Evolutionary Heterogeneity with Change-Point Models, Gaussian Markov Random Fields, and Markov Chain Induced Counting Processes

Suchard, M.

2006

McCarthy, Michelle

Neocortical Mechanisms Mediating Electroencelphalographic Oscillations: A Biomathematical Analysis of Anesthesia-Induced Paradoxical Excitation

Newton, C., Brown, E.

2007

Bauman, Lara

STL Variance Component Models

Lange, K.

2007

Aten, Jason

Causal not Confounded Gene Networks: Inferring Acyclic and Non-acyclic Gene Bayesian Networks in mRNA Expression Studies using Recursive V-Structures, Genetic Variation, and Orthogonal Causal Anchor Structural Equation Models

Lange, K.
Horvath, S

2008

Ayers, Kristin

Methods for Haplotype Construction and Their Applications

Lange, K.

2008

Alekseyenko, Alexander

Computational, comparative and stochastic modeling approaches to evolution of alternatively spliced exons

Marc Suchard and Christopher Lee

2008

Marshall, John

The dynamics of transposable elements in genetically modified mosquito vectors

Tom Chou and Charles Taylor

2008

O'Brien, John D.

Robust Statistical Methods for Estimating the Distance and the Rate of Change among Molecular Sequences Sampled from Rapidly-Evolving Organisms

Marc Suchard and Zhen-Su She

2008

Rovetti, Robert

Stochastic models of intracellular calcium release and alternans

Tom Chou and Zhilin Qu

2008


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