Better Living Through Control: With Applications to Neural and Cardiac Systems

Date Thursday November 10, 2016 at 4:00 PM
Location A2-342 MDCC, Moss Auditorium, Marion Davies Children Clinic
Speaker Jeff Moehlis, Ph.D., Professor, Department of Mechanical Engineering, University of California, Santa Barbara
Sponsoring Dept UCLA Biomathematics
Abstract Some brain disorders are hypothesized to have a dynamical origin; in particular, it has been been hypothesized that some symptoms of Parkinson’s disease are due to pathologically synchronized neural activity in the motor control region of the brain. We have developed a procedure for determining an optimal electrical deep brain stimulus which desynchronizes the activity of a group of neurons by maximizing the Lyapunov exponent associated with their phase dynamics, work that could lead to an improved method for treating Parkinson’s disease. The use of related control methods for treating other medical disorders, including cardiac arrhythmias such as alternans, will also be discussed.
Flyer Jeff_Moehlis_20161110.pdf